Structure of PDB 6exh Chain A

Receptor sequence
>6exhA (length=348) Species: 239 (Flavobacterium sp.) [Search protein sequence]
LTLEIPTSPLIIKITQQERNILSNVGNLLVKAFGNYENPDYIASLHLHAF
QLLPERITRILSQFGSDFSAEQYGAIVFQGLIEVDQDDLGPTPPNWQGAD
YGKLNKYGFICSLLHGAVPSKPVQYYAQRKGGGLLHAVIPDEKMAATQTG
SGSKTDLFVHTEDAFLSNQADFLSFLYLRNEERVPSTLYSIRSHGKMNPV
MKKLFEPIYQCPKDANSGPTASVLYGNRELPFIRFDAAEQIFNENAGQTS
EALGNLMDFWDEAKTLINSDYIPNSGDLIFVNNHLCAHGRSAFIAGQRIE
NGEIIKCERRQMLRMMSKTSLIHIRSVTRTDDPYFIMEEHLGKIFDLD
3D structure
PDB6exh Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE A H176 E178 H312 H160 E162 H288
BS02 LYO A R145 G166 S167 D230 R338 R129 G150 S151 D214 R314
Gene Ontology
Molecular Function
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:6exh, PDBe:6exh, PDBj:6exh
PDBsum6exh
PubMed30410048
UniProtJ3BZS6|LYS4O_FLASC L-lysine 4-hydroxylase (Gene Name=PMI10_03368)

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