Structure of PDB 6ex9 Chain A

Receptor sequence
>6ex9A (length=140) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAG
RWPVKTIHTDNGSNFTGATVRAACDWAGIKQEFQGVVESMNKELKKIIGQ
VRDQAEHLKTAVQMAVFIHNKKRKGYSAGERIVDIIATDI
3D structure
PDB6ex9 Multimerization of HIV-1 integrase hinges on conserved SH3-docking platforms
ChainA
Resolution2.014 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L68 E69 G163 R166 D167 L12 E13 G99 R102 D103
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:6ex9, PDBe:6ex9, PDBj:6ex9
PDBsum6ex9
PubMed
UniProtP04585|POL_HV1H2 Gag-Pol polyprotein (Gene Name=gag-pol)

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