Structure of PDB 6euv Chain A

Receptor sequence
>6euvA (length=277) Species: 392809 (Influenza A virus (A/Victoria/3/1975(H3N2))) [Search protein sequence]
NDDIDQSLIIAARNIVRRASVSADPLASLLEMCHSTQIGGTRMVDILRQN
PTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQT
LKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVA
MVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGI
EHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVSTERVVVSIDRFLRVR
DQRGNVLLSPEEVSETHGTERLTITYS
3D structure
PDB6euv Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 21G A F323 R355 H357 E361 K376 F404 Q406 M431 N510 V511 F72 R104 H106 E110 K125 F153 Q155 M180 N255 V256 PDBbind-CN: -logKd/Ki=8.62,Kd=2.4nM
BS02 21G A H285 R293 R299 H34 R42 R48 PDBbind-CN: -logKd/Ki=8.62,Kd=2.4nM
External links
PDB RCSB:6euv, PDBe:6euv, PDBj:6euv
PDBsum6euv
PubMed29202182
UniProtP31345|PB2_I75A3 Polymerase basic protein 2 (Gene Name=PB2)

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