Structure of PDB 6esl Chain A

Receptor sequence
>6eslA (length=359) Species: 446 (Legionella pneumophila) [Search protein sequence]
SPVHEQLQVPQCLAAKITVPHKILAENKEFKIIDVLSSDVETLTILADKV
SCGHFVNVSHKLQQQSAQKLLQGVSKLVYEIKHEEEVNAALKEIVSDNIW
QTLTHMTSYYNRSATKDTGVETANWLKSKFEQMAVEYGRTDTSTFFVKTG
WYKQPSLVTVIGKDIKAPAIVIGAHMDTLDGRMPGAGDDGSGSSSIMEAA
RVILSSKTTFKRPIYFIWYAAEERGLVGSQHVVQHFQEQSIPVKAVVQFD
MTGYRNDANDPTMWVFTDYTDRDLSNYLAKLIDHYIHVPVDYSRCGYGCS
DHASWNEEDIPAAFPCETSFADHNPYIHTSSDKMDLLNLEHMTNFSKLAV
AFAIELASE
3D structure
PDB6esl Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition duringLegionella pneumophilaIntracellular Infection of Amoebas.
ChainA
Resolution1.87 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H194 D207 E241 E242 D269 H347
Catalytic site (residue number reindexed from 1) H175 D188 E222 E223 D250 H328
Enzyme Commision number 3.4.11.10: bacterial leucyl aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D207 E242 H347 D188 E223 H328
BS02 ZN A H194 D207 D269 H175 D188 D250
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6esl, PDBe:6esl, PDBj:6esl
PDBsum6esl
PubMed29666285
UniProtQ5ZRR6

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