Structure of PDB 6er4 Chain A

Receptor sequence
>6er4A (length=194) Species: 411470 (Mediterraneibacter gnavus ATCC 29149) [Search protein sequence]
MADIGSVLQKEGIEISEGTGYDLSKEPGAATVKALEQGTIVISYKTTSEN
AIQSLLSVGNGTKGNQDRHFHLYITNAGGVGMELRNTDGEFKYTLDCPAA
VRGSYKGERVSNTVALKADKENKQYKLFANGELIATLDQEAFKFISDITG
VDNVMLGGTMRQGTVAYPFGGSIERMQVYRDVLSDDELIAVTGK
3D structure
PDB6er4 Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus.
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A D110 D131 D67 D88 PDBbind-CN: -logKd/Ki=2.77,Kd=1.70mM
BS02 SIA A I95 E126 R128 K135 R204 Y210 I52 E83 R85 K92 R161 Y167 PDBbind-CN: -logKd/Ki=2.77,Kd=1.70mM
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6er4, PDBe:6er4, PDBj:6er4
PDBsum6er4
PubMed29259165
UniProtA7B557

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