Structure of PDB 6epx Chain A

Receptor sequence
>6epxA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB6epx Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
ChainA
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BQW A Y1063 N1064 G1070 D1071 Y85 N86 G92 D93
BS02 BQW A C1079 D1083 C101 D105
External links
PDB RCSB:6epx, PDBe:6epx, PDBj:6epx
PDBsum6epx
PubMed32832026
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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