Structure of PDB 6epw Chain A

Receptor sequence
>6epwA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB6epw Hitting a moving target: simulation and crystallography study of ATAD2 bromodomain blockers
ChainA
Resolution1.924 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BQ8 A V1008 V1013 Y1063 N1064 G1070 D1071 V30 V35 Y85 N86 G92 D93
BS02 BQ8 A P1015 Y1021 V1022 I1025 P1028 P37 Y43 V44 I47 P50
External links
PDB RCSB:6epw, PDBe:6epw, PDBj:6epw
PDBsum6epw
PubMed
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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