Structure of PDB 6epv Chain A

Receptor sequence
>6epvA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB6epv Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
ChainA
Resolution1.793 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BQT A Y1063 N1064 G1070 D1071 Y85 N86 G92 D93 BindingDB: IC50=>150000nM
External links
PDB RCSB:6epv, PDBe:6epv, PDBj:6epv
PDBsum6epv
PubMed32832026
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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