Structure of PDB 6epj Chain A

Receptor sequence
>6epjA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB6epj Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
ChainA
Resolution1.652 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BOH A V1008 Y1063 N1064 G1070 D1071 V30 Y85 N86 G92 D93 BindingDB: IC50=>150000nM
BS02 BOH A Y1086 I1089 E1095 Y108 I111 E117 BindingDB: IC50=>150000nM
External links
PDB RCSB:6epj, PDBe:6epj, PDBj:6epj
PDBsum6epj
PubMed32832026
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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