Structure of PDB 6eol Chain A

Receptor sequence
>6eolA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
MLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB6eol Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-pi , and Halogen Bond Interactions.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BKH A R144 I145 A146 H158 N160 R162 N174 W181 E184 S237 G238 R32 I33 A34 H46 N48 R50 N62 W69 E72 S125 G126 MOAD: Kd=0.037uM
PDBbind-CN: -logKd/Ki=7.43,Kd=0.037uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:6eol, PDBe:6eol, PDBj:6eol
PDBsum6eol
PubMed29194992
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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