Structure of PDB 6eog Chain A

Receptor sequence
>6eogA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
MLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB6eog Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-pi , and Halogen Bond Interactions.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BKK A R144 I145 A146 H158 R162 N174 W181 E184 S237 G238 R32 I33 A34 H46 R50 N62 W69 E72 S125 G126 MOAD: Kd=1.6uM
PDBbind-CN: -logKd/Ki=5.80,Kd=1.60uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:6eog, PDBe:6eog, PDBj:6eog
PDBsum6eog
PubMed29194992
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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