Structure of PDB 6enz Chain A

Receptor sequence
>6enzA (length=487) Species: 10090 (Mus musculus) [Search protein sequence]
VDGVVLNGPQTDVKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWQPPEQ
LRQLLDLEMRDTGESQDKLLKLCQDVIHFSVKTNHPRFFNQLYAGLDYYS
LAARIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPG
GSVSNMCAMNLARYRHCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFL
GIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLG
AFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVAW
NPHKMLMAGIQCSALLVKDKSDLLKKCYSAKATDKFYDVSYDTGDKSIQC
SRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLLME
PEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQ
PHRGKVNFFRQVVISPQVSREDMDFLLDEIDSLGRDM
3D structure
PDB6enz Structure of the mouse acidic amino acid decarboxylase GADL1.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.11: aspartate 1-decarboxylase.
4.1.1.29: sulfinoalanine decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A G160 G161 S162 H200 T257 D282 S284 K314 G150 G151 S152 H190 T247 D272 S274 K304
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0004068 aspartate 1-decarboxylase activity
GO:0004782 sulfinoalanine decarboxylase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0008150 biological_process
GO:0019752 carboxylic acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6enz, PDBe:6enz, PDBj:6enz
PDBsum6enz
PubMed29372909
UniProtQ80WP8|GADL1_MOUSE Acidic amino acid decarboxylase GADL1 (Gene Name=Gadl1)

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