Structure of PDB 6eje Chain A

Receptor sequence
>6ejeA (length=695) Species: 9606 (Homo sapiens) [Search protein sequence]
QPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFCP
LEGKANKNSVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYI
HVDKRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDL
LEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARF
IRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRFVEYVTF
STDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRK
LGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEAVVNQEI
IGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLYHSFARL
GLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKHHATNLA
VSKLETLETWVMPKKVFKIFGRLQFSEVGTDWDAKERLFRNFGGLLGPMD
EPVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHYKPPLNL
PLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKLHNGPLR
NAYMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWLDSLVGGMW
TAMDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRLR
3D structure
PDB6eje Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
ChainA
Resolution2.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.26: protein xylosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H451 K461 Q462 S493 E529 W555 R557 W571 C572 G573 H193 K203 Q204 S235 E271 W297 R299 W313 C314 G315
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0030158 protein xylosyltransferase activity
Biological Process
GO:0030166 proteoglycan biosynthetic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6eje, PDBe:6eje, PDBj:6eje
PDBsum6eje
PubMed29681470
UniProtQ86Y38|XYLT1_HUMAN Xylosyltransferase 1 (Gene Name=XYLT1)

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