Structure of PDB 6ejd Chain A

Receptor sequence
>6ejdA (length=693) Species: 9606 (Homo sapiens) [Search protein sequence]
QPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFCP
LEGKANVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVD
KRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDLLEM
TDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARFIRK
QGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRFVEYVTFSTD
DLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGC
KCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEAVVNQEIIGQ
LDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLYHSFARLGLR
RAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKHHATNLAVSK
LETLETWVMPKKVFKIDFGRLQFSEVGTDWDAKERLFRNFGGLLGPMDEP
VGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHYKPPLNLPL
RPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKLHNGPLRNA
YMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWLDSLVGGMWTA
MDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRLR
3D structure
PDB6ejd Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
ChainA
Resolution2.684 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.26: protein xylosyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K461 Q462 S493 E529 W555 R557 W571 C572 K200 Q201 S232 E268 W294 R296 W310 C311
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0030158 protein xylosyltransferase activity
Biological Process
GO:0030166 proteoglycan biosynthetic process
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6ejd, PDBe:6ejd, PDBj:6ejd
PDBsum6ejd
PubMed29681470
UniProtQ86Y38|XYLT1_HUMAN Xylosyltransferase 1 (Gene Name=XYLT1)

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