Structure of PDB 6ej9 Chain A

Receptor sequence
>6ej9A (length=701) Species: 9606 (Homo sapiens) [Search protein sequence]
DQPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFC
PLEGKANKNVWDEDSVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHK
DHFYYIHVDKRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYL
QSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHG
RDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRF
VEYVTFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRI
TNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEA
VVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLY
HSFARLGLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKH
HATNLAVSKLETLETWVMPKKVFKIFGRLQFSEVGTDWDAKERLFRNFGG
LLGPMDEPVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHY
KPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKL
HNGPLRNAYMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWLDS
LVGGMWTAMDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRL
R
3D structure
PDB6ej9 Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
ChainA
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.26: protein xylosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H451 K461 Q462 R466 S493 E529 W555 R557 W571 C572 G573 C574 H199 K209 Q210 R214 S241 E277 W303 R305 W319 C320 G321 C322
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0030158 protein xylosyltransferase activity
Biological Process
GO:0030166 proteoglycan biosynthetic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ej9, PDBe:6ej9, PDBj:6ej9
PDBsum6ej9
PubMed29681470
UniProtQ86Y38|XYLT1_HUMAN Xylosyltransferase 1 (Gene Name=XYLT1)

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