Structure of PDB 6ej8 Chain A

Receptor sequence
>6ej8A (length=703) Species: 9606 (Homo sapiens) [Search protein sequence]
DQPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFC
PLEGKANKNQWDEDSVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHK
DHFYYIHVDKRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYL
QSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHG
RDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRF
VEYVTFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRI
TNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEA
VVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLY
HSFARLGLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKH
HATNLAVSKLETLETWVMPKKVFKIASPGRLQFSEVGTDWDAKERLFRNF
GGLLGPMDEPVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFT
HYKPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEAL
KLHNGPLRNAYMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWL
DSLVGGMWTAMDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDG
RLR
3D structure
PDB6ej8 Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
ChainA
Resolution2.09 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.26: protein xylosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H451 K461 Q462 S493 E529 W555 R557 W571 C572 G573 C574 H199 K209 Q210 S241 E277 W303 R305 W319 C320 G321 C322
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0030158 protein xylosyltransferase activity
Biological Process
GO:0030166 proteoglycan biosynthetic process
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ej8, PDBe:6ej8, PDBj:6ej8
PDBsum6ej8
PubMed29681470
UniProtQ86Y38|XYLT1_HUMAN Xylosyltransferase 1 (Gene Name=XYLT1)

[Back to BioLiP]