Structure of PDB 6e8f Chain A

Receptor sequence
>6e8fA (length=343) Species: 9606 (Homo sapiens) [Search protein sequence]
PMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQPGI
LYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG
HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTS
PLRIVALDKDIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITRYLTL
LQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYD
VYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLI
TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP
3D structure
PDB6e8f Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
ChainA
Resolution2.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N368 Q370 D409 D411 D471 N117 Q119 D158 D160 D220
BS02 CA A E385 E458 D487 A488 D490 D523 E134 E207 D236 A237 D239 D272
BS03 CA A E385 D456 E458 D490 E134 D205 E207 D239
BS04 CA A N489 N491 D521 D523 N527 D573 N238 N240 D270 D272 N276 D322
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6e8f, PDBe:6e8f, PDBj:6e8f
PDBsum6e8f
PubMed32963095
UniProtQ96QU1|PCD15_HUMAN Protocadherin-15 (Gene Name=PCDH15)

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