Structure of PDB 6e7x Chain A

Receptor sequence
>6e7xA (length=358) Species: 8355 (Xenopus laevis) [Search protein sequence]
DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLQATSVTHRPNAI
QMALSVCEDLISSQVYAILVSHPPAHLTPTPISYTAGFYRIPVIGLTTRM
SIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRA
AQKKLETLLEGGPKADKVLQFEPGTKNLTALLLEAKELEARVIILSASED
DATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYAPDGIIGLQLINGKN
ESAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLM
SSKYPDGVTGRIEFNEDGDRKFAQYSIMNLQNRKLVQVGIFNGSYIIQND
RKIIWPGG
3D structure
PDB6e7x Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
ChainA
Resolution2.58 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 T97 A Y109 F113 S132 I133 L135 Y84 F88 S107 I108 L110 PDBbind-CN: -logKd/Ki=6.76,Kd=175nM
External links
PDB RCSB:6e7x, PDBe:6e7x, PDBj:6e7x
PDBsum6e7x
PubMed
UniProtA0A1L8F5J9|NMDZ1_XENLA Glutamate receptor ionotropic, NMDA 1 (Gene Name=grin1)

[Back to BioLiP]