Structure of PDB 6e6x Chain A

Receptor sequence
>6e6xA (length=175) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
MAMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMY
SDFGHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEMATKADYTLDEESRARI
KTRLFTIRQEMASRSLWDSFRQSER
3D structure
PDB6e6x SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A H41 D108 E119 I120 H43 D89 E100 I101
BS02 MN A E80 D108 E61 D89
BS03 HWM A K34 H41 E80 D108 E119 K134 K36 H43 E61 D89 E100 K115
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:6e6x, PDBe:6e6x, PDBj:6e6x
PDBsum6e6x
PubMed31536340
UniProtC3W5S0

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