Structure of PDB 6e4q Chain A

Receptor sequence
>6e4qA (length=505) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
GGGPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPD
PRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIG
KIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHA
KSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHY
RDSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSID
REFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKR
SPYKWRNVLKKNSVRLAEVWMDEYSQYYYHRIGNDKGDWGDVSDRRKLRN
DLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNLGYGGRTCLDAPAGKKHQ
KKAVGTYPCHRQGGNQYWMLSKAGEIRRDDSCLDYAGKDVTLFGCHGGKG
NQFWTYRENTKQLHHGTSGKCLAISESKDKLLMEECSASLSRQQWTLENY
DSSKL
3D structure
PDB6e4q A molecular switch orchestrates enzyme specificity and secretory granule morphology.
ChainA
Resolution2.799 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.41: polypeptide N-acetylgalactosaminyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A D301 H303 H437 D159 H161 H295
BS02 UDP A C216 F217 D249 R278 L281 D301 S302 H303 H437 Y445 C74 F75 D107 R136 L139 D159 S160 H161 H295 Y303
External links
PDB RCSB:6e4q, PDBe:6e4q, PDBj:6e4q
PDBsum6e4q
PubMed30158631
UniProtQ8MRC9|GALT9_DROME Putative polypeptide N-acetylgalactosaminyltransferase 9 (Gene Name=Pgant9)

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