Structure of PDB 6e3a Chain A

Receptor sequence
>6e3aA (length=180) Species: 203119 (Acetivibrio thermocellus ATCC 27405) [Search protein sequence]
LIDYSKLSKEVAYALRHAPWEYGLELDAEGWVDINQLLSSLHECEKWKKV
SEHDLHVMIEKSDKKRYEISNGKIRALYGHSIPQRIIKEQKCPPEVLYHG
TARRFVKSIKEKGLQPQGRQYVHLSADVETALQVGKRRDIKPVLLIVNAL
EAWSEGIKFYLGNDKVWLADAIPSKYIRFE
3D structure
PDB6e3a Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A S10 K11 E12 A14 R18 H19 C46 R68 R121 S8 K9 E10 A12 R16 H17 C44 R66 R119
BS02 HQG A R18 K66 R68 Y80 H101 T103 F107 S110 I111 L116 Q117 Q119 R121 V136 R139 R140 R16 K64 R66 Y78 H99 T101 F105 S108 I109 L114 Q115 Q117 R119 V134 R137 R138
Gene Ontology
Molecular Function
GO:0000215 tRNA 2'-phosphotransferase activity
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

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Molecular Function
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Biological Process
External links
PDB RCSB:6e3a, PDBe:6e3a, PDBj:6e3a
PDBsum6e3a
PubMed30644400
UniProtA3DJX6|KPTA_ACET2 Probable RNA 2'-phosphotransferase (Gene Name=kptA)

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