Structure of PDB 6e33 Chain A

Receptor sequence

>6e33A (length=58) Species: 284812 (Schizosaccharomyces pombe 972h-)

GKVKKRLPQAKRACAKCQKDNKKCDDARPCQRCIKAKTDCIDLPRKKRPT
GVRRGPYK

3D structure

• PDB: 6e33 Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis.
• Chain: A
• Resolution: 1.705 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	V281 K282 K283 Q287 D298 N299 K300 R326 G329 V330 R331 R332 G333 P334 Y335	V3 K4 K5 Q9 D20 N21 K22 R48 G51 V52 R53 R54 G55 P56 Y57
BS02	dna	A	K282 R284 Q287 A288 R290 A291 Q296 N299 K300 K301 C302 R323 K324 R332 Y335 K336	K4 R6 Q9 A10 R12 A13 Q18 N21 K22 K23 C24 R45 K46 R54 Y57 K58
BS03	ZN	A	C292 C308 C311 C318	C14 C30 C33 C40
BS04	ZN	A	C292 C295 C302 C308	C14 C17 C24 C30

Gene Ontology

Molecular Function

• GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
• GO:0008270 zinc ion binding

Biological Process

• GO:0006355 regulation of DNA-templated transcription

External links

• PDB: RCSB:6e33, PDBe:6e33, PDBj:6e33
• PDBsum: 6e33
• PubMed: 30212894
• UniProt: O13658|YBCB_SCHPO Uncharacterized transcriptional regulatory protein C27B12.11c (Gene Name=pi067)