Structure of PDB 6e0l Chain A

Receptor sequence
>6e0lA (length=292) Species: 762570 (Rhodothermus marinus SG0.5JP17-172) [Search protein sequence]
PVPESQLERWSHQGATTTAKKTHESIRAALDRYKWPKGKPEVYLQGSYKN
STNIRGDSDVDVVVQLNSVFMNNLTAEQKRRFGFVKSDYTWNDFYSDVER
ALTDYYGASKVRRGRKTLKVETTYLPADVVVCIQYRKYPPNRKSEDDYIE
GMTFYVPSEDRWVVNYPKLHYENGAAKNQQTNEWYKPTIRMFKNARTYLI
EQGAPQDLAPSYFLECLLYNVPDSKFGGTFKDTFCSVINWLKRADLSKFR
CQNGQDDLFGEFPEQWSEEKARRFLRYMDDLWTGWGQGSHHH
3D structure
PDB6e0l Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APC A Q46 G47 S48 D62 S212 Y213 E265 Q45 G46 S47 D61 S211 Y212 E264
BS02 2KH A R116 K117 T118 K120 V131 N166 R115 K116 T117 K119 V130 N165
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6e0l, PDBe:6e0l, PDBj:6e0l
PDBsum6e0l
PubMed30787435
UniProtG2SLH8|CDNE_RHOMG Cyclic UMP-AMP synthase (Gene Name=cdnE)

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