Structure of PDB 6dzw Chain A

Receptor sequence
>6dzwA (length=537) Species: 9606 (Homo sapiens) [Search protein sequence]
RETWGKKVDFLLSVIGYAVDLGNVWRFPYICAQNGGGAFLLPYTIMAIFG
GIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNT
IMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPA
EEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSG
KVVWVTATFPYIALSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWID
AAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFV
IFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFF
LMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSL
VTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEM
LGFSPGWFWRICWVAISPLFLLFIIASFLMSPPQLRLFQYNYPYWSIILG
YAIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPE
3D structure
PDB6dzw Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
ChainA
Resolution4.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8PR A Y95 D98 I172 S438 T439 G442 Y17 D20 I94 S360 T361 G364 BindingDB: Ki=0.42nM,Kd=0.130000nM,IC50=0.200000nM
Gene Ontology

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Cellular Component
External links
PDB RCSB:6dzw, PDBe:6dzw, PDBj:6dzw
PDBsum6dzw
PubMed31019304
UniProtP31645|SC6A4_HUMAN Sodium-dependent serotonin transporter (Gene Name=SLC6A4)

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