Structure of PDB 6dys Chain A

Receptor sequence
>6dysA (length=213) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MLKMEAVPLRLEHRQEVIDIIVASFYNKADLEQWLKPGVLRTDYSDILND
IWNVLVERDLSFVVYDTNTDRIIGTALNFDARNEPEVDIKSKLLIVFEFL
EFCEGPIRDNYLPKGLNQILHSFMMGTAEKLNPRENIACMHFMEHEVLRV
AREKQFAGIFTTNTSPLTQQLADVYHYKTLLNFQVNEYVHSDGSRPFGDA
PDEQRAIVHWKEV
3D structure
PDB6dys Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HJ1 A F689 E696 V760 L764 F787 M788 M789 T825 T826 N827 F25 E32 V96 L100 F123 M124 M125 T161 T162 N163 MOAD: Kd=56.4uM
PDBbind-CN: -logKd/Ki=4.25,Kd=56.4uM
External links
PDB RCSB:6dys, PDBe:6dys, PDBj:6dys
PDBsum6dys
PubMed30705105
UniProtQ9VDC6|EBO_DROME Beta-alanyl-bioamine nonribosomal peptide synthetase ebony (Gene Name=e)

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