Structure of PDB 6dxz Chain A

Receptor sequence
>6dxzA (length=95) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
PGPPLFNVSLDVAPELRWLPVLRHYDVELVRAAVAQVIGDRVPKWVLALI
EKGALKLERLLPPPFTAEIRGMCDFLNLSLADGLLVNLAYEYSAF
3D structure
PDB6dxz Molecular mechanism of activation of the immunoregulatory amidase NAAA.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.23: ceramidase.
3.5.1.60: N-(long-chain-acyl)ethanolamine deacylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TRT A V78 I82 L89 E123 Y124 V46 I50 L57 E91 Y92
BS02 TRT A A45 E47 D106 A13 E15 D74
BS03 WTF A A65 V66 V118 Y122 F127 A33 V34 V86 Y90 F95
External links
PDB RCSB:6dxz, PDBe:6dxz, PDBj:6dxz
PDBsum6dxz
PubMed30301806
UniProtG1T7U7|NAAA_RABIT N-acylethanolamine-hydrolyzing acid amidase (Gene Name=NAAA)

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