Structure of PDB 6dwy Chain A

Receptor sequence

>6dwyA (length=483) Species: 7370 (Musca domestica) [Search protein sequence]

RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAE
YGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATID
LWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKA
IFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEE
TPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSIL
DNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSP
SLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHY
TAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEF
YRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFS
LAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK

3D structure

PDB

6dwy Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	P108 F109 S110 K372 Q375 S378 R573 K605	P28 F29 S30 K292 Q295 S298 R447 K479
BS02	dna	A	W182 T183 R218 T220 A251 N252 K255 H268 R308 S309 S310 K312 R318 W319 Q375 E572 R573 S576	W102 T103 R138 T140 A171 N172 K175 H188 R228 S229 S230 K232 R238 W239 Q295 E446 R447 S450
BS03	dna	A	D248 R249 N272	D168 R169 N192
BS04	CA	A	D180 D248	D100 D168

Gene Ontology

	Molecular Function
GO:0046983	protein dimerization activity

View graph for
Molecular Function

External links

PDB	RCSB:6dwy, PDBe:6dwy, PDBj:6dwy
PDBsum	6dwy
PubMed	30239795
UniProt	Q25438

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