Structure of PDB 6dvo Chain A

Receptor sequence
>6dvoA (length=352) Species: 7955 (Danio rerio) [Search protein sequence]
ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPAR
LATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCA
LLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALT
ARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAF
FPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIARE
FAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILE
GGYNLTSISESMSMCTSMLLGDSPPSLPLKTSATVSINNVLRAHAPFWSS
LR
3D structure
PDB6dvo Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D612 H614 D705 D170 H172 D263
BS02 PRO A E515 T540 E73 T98
BS03 HBV A P464 H573 H574 G582 F583 D612 H614 F643 Y745 P22 H131 H132 G140 F141 D170 H172 F201 Y303 MOAD: ic50=60nM
PDBbind-CN: -logKd/Ki=7.22,IC50=60nM
External links