Structure of PDB 6du2 Chain A

Receptor sequence
>6du2A (length=180) Species: 9365 (Erinaceus europaeus) [Search protein sequence]
QYLLPEAKAQDSDKICVVINLDETLVHSSFKPVNNADFIIPVEIDGVVHQ
VYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARL
FRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWF
DNMSDTELHDLLPFFEQLSRVDDVYSVLRQ
3D structure
PDB6du2 Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A N96 D98 T152 A153 S154 R178 F183 G186 Y188 N20 D22 T76 A77 S78 R102 F107 G110 Y112
BS02 MG A N96 D98 N207 N20 D22 N131
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:6du2, PDBe:6du2, PDBj:6du2
PDBsum6du2
PubMed30217818
UniProtA0A1S2ZIM2

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