Structure of PDB 6ds6 Chain A

Receptor sequence
>6ds6A (length=53) Species: 9606 (Homo sapiens) [Search protein sequence]
ARTKQTQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKME
KLG
3D structure
PDB6ds6 The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C14 C17 C36 C39 C14 C17 C36 C39
BS02 ZN A C27 C30 H45 H47 C27 C30 H45 H47
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6ds6, PDBe:6ds6, PDBj:6ds6
PDBsum6ds6
PubMed30150647
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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