Structure of PDB 6dru Chain A

Receptor sequence

>6druA (length=718) Species: 5061 (Aspergillus niger) [Search protein sequence]

TYFAPNSTGLRIQHGFETILIQPFGYDGFRVRAWPFRPPSGNEISFIYDP
PIEGYEDTAHGMSYDTATTGTEPRTLRNGNIILRTTGWGGTTAGYRLSFY
RVNDDGSETLLTNEYAPLKSLNPRYYYWPGPGAEFSAEFSFSATPDEQIY
GTGTQQDHMINKKGSVIDMVNFNSYIPTPVFMSNKGYAFIWNMPAEGRME
FGTLRTRFTAASTTLVDYVIVAAQPGDYDTLQQRISALTGRAPAPPDFSL
GYIQSKLRYENQTEVELLAQNFHDRNIPVSMIVIDYQSWAHQGDWALDPR
LWPNVAQMSARVKNLTGAEMMASLWPSVADDSVNYAALQANGLLSATRDG
PGTTDSWNGSYIRNYDSTNPSARKFLWSMLKKNYYDKGIKNFWIDQADGG
ALGEAYENNGQSTYIESIPFTLPNVNYAAGTQLSVGKLYPWAHQQAIEEG
FRNATDTKEGSACDHVSLSRSGYIGSQRFCSMIWSGDTTSVWDTLAVQVA
SGLSAAATGWGWWTVDAGGFEVDSTVWWSGNIDTPEYRELYVRWLAWTTF
LPFMRTHGSRTCYFQDAYTCANEPWSYGASNTPIIVSYIHLRYQLGAYLK
SIFNQFHLTGRSIMRPLYMDFEKTDPKISQLVSSNSNYTTQQYMFGPRLL
VSPVTLPNVTEWPVYLPQTGQNNTKPWTYWWTNETYAGGQVVKVPAPLQH
IPVFHLGSREELLSGNVF

3D structure

PDB

6dru Crystal Structure of alpha-Xylosidase fromAspergillus nigerin Complex with a Hydrolyzed Xyloglucan Product and New Insights in Accurately Predicting Substrate Specificities of GH31 Family Glycosidases.

Chain

Resolution

2.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.2.1.177: alpha-D-xyloside xylohydrolase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	BMA	A	Q565 D566	Q565 D566
BS02	MAN	A	F564 Q565	F564 Q565
BS03	MAN	A	N261 P303	N261 P303
BS04	MAN	A	D523 T525	D523 T525
BS05	BGC	A	F520 S559	F520 S559
BS06	BGC	A	Y286 Q396 E404 Y406 N409	Y286 Q396 E404 Y406 N409
BS07	MAN	A	L110 N113	L110 N113
BS08	MAN	A	N113 A116	N113 A116
BS09	XYS	A	D285 Y286 W393 D395 R470 D487 F520 H557	D285 Y286 W393 D395 R470 D487 F520 H557

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798	hydrolase activity, acting on glycosyl bonds
GO:0030246	carbohydrate binding
GO:0061634	alpha-D-xyloside xylohydrolase

	Biological Process
GO:0005975	carbohydrate metabolic process

	Cellular Component
GO:0005576	extracellular region
GO:0016020	membrane

View graph for
Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6dru, PDBe:6dru, PDBj:6dru
PDBsum	6dru
PubMed	32161692
UniProt	A2QTU5\|XYLA_ASPNC Alpha-xylosidase A (Gene Name=axlA)

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