Structure of PDB 6drb Chain A

Receptor sequence
>6drbA (length=278) Species: 632 (Yersinia pestis) [Search protein sequence]
SPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCRR
QTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLA
SSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTI
REAGQKTISVPVVHVTTWVVSSEVTKALASLVDQTAETKRNMYESKGSSA
VADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQR
NGIMVQKDEQLDVLIKLAEGQGRPLLNS
3D structure
PDB6drb A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
ChainA
Resolution2.745 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E290 W354 H402 C403 R409 T410
Catalytic site (residue number reindexed from 1) E104 W168 H212 C213 R219 T220
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WO4 A C403 R404 A405 G408 R409 C213 R214 A215 G218 R219
Gene Ontology
Molecular Function
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6drb, PDBe:6drb, PDBj:6drb
PDBsum6drb
PubMed30110154
UniProtO68720

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