Structure of PDB 6dmj Chain A

Receptor sequence
>6dmjA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB6dmj qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 53W A W81 P82 K91 L92 L94 N140 W40 P41 K50 L51 L53 N99 BindingDB: IC50=2.4e+3nM,Kd=7.8e+2nM
External links
PDB RCSB:6dmj, PDBe:6dmj, PDBj:6dmj
PDBsum6dmj
PubMed30457858
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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