Structure of PDB 6dhw Chain A

Receptor sequence
>6dhwA (length=170) Species: 9606 (Homo sapiens) [Search protein sequence]
KISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLT
LEQALQFWKQFDKGYSYNIRHSFDYTPFSCLKIILSNPPSQGDYHGCPFR
HSDPELLKQKLQSYKISPGGISQILDLVKGTHYQVACQKYFEMIHNVDDC
GFSLNHPNQFFCESQRILNG
3D structure
PDB6dhw Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs.
ChainA
Resolution2.013 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A P285 C287 C367 I370 C384 F386 Q421 C424 L441 P444 P16 C18 C80 I83 C97 F99 Q134 C137 L154 P157
Gene Ontology
Biological Process
GO:0006269 DNA replication, synthesis of primer

View graph for
Biological Process
External links
PDB RCSB:6dhw, PDBe:6dhw, PDBj:6dhw
PDBsum6dhw
PubMed30562384
UniProtP49643|PRI2_HUMAN DNA primase large subunit (Gene Name=PRIM2)

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