Structure of PDB 6dgf Chain A

Receptor sequence
>6dgfA (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHT
ALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFL
RFLLDGLHNEVNRVDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSL
TCTDCGYCSTVFDPFWDLSLPIAKYPEVTLMDCMRLFTKEDVLDGDEKPT
CCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRD
LDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFND
SSVTPMSSSQVRTSDAYLLFYELASPPSRM
3D structure
PDB6dgf Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases.
ChainA
Resolution2.34 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C425 C428 C476 C479 C152 C155 C201 C204
Gene Ontology
Molecular Function
GO:0004843 cysteine-type deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6dgf, PDBe:6dgf, PDBj:6dgf
PDBsum6dgf
PubMed30763569
UniProtO75604|UBP2_HUMAN Ubiquitin carboxyl-terminal hydrolase 2 (Gene Name=USP2)

[Back to BioLiP]