Structure of PDB 6ddj Chain A

Receptor sequence
>6ddjA (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMQDPEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDII
KHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMAR
KLQDVFEFRYAKMPD
3D structure
PDB6ddj Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer.
ChainA
Resolution1.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G7V A W370 P371 N429 H433 V435 W30 P31 N89 H93 V95
External links
PDB RCSB:6ddj, PDBe:6ddj, PDBj:6ddj
PDBsum6ddj
PubMed32651255
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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