Structure of PDB 6dcz Chain A

Receptor sequence
>6dczA (length=180) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
AMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYS
DFGALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENR
FIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEE
SRARIKTRLFTIRQEMASRSLWDSFRQSER
3D structure
PDB6dcz Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease.
ChainA
Resolution2.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G5Y A H41 E80 D108 E119 K134 H42 E64 D92 E103 K118 PDBbind-CN: -logKd/Ki=7.17,IC50=0.068uM
BS02 MN A E80 D108 E64 D92
BS03 MN A H41 D108 E119 I120 H42 D92 E103 I104
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:6dcz, PDBe:6dcz, PDBj:6dcz
PDBsum6dcz
PubMed30351002
UniProtC3W5S0

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