Structure of PDB 6dco Chain A

Receptor sequence
>6dcoA (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
PLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYR
RAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCV
ESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNN
3D structure
PDB6dco Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
ChainA
Resolution2.198 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E96 F97 R100 Y101 F105 L108 L112 S122 Q125 V126 E129 L130 D133 N136 G138 R139 Y195 E44 F45 R48 Y49 F53 L56 L60 S70 Q73 V74 E77 L78 D81 N84 G86 R87 Y143
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:6dco, PDBe:6dco, PDBj:6dco
PDBsum6dco
PubMed30626284
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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