Structure of PDB 6d6t Chain A

Receptor sequence
>6d6tA (length=333) Species: 9606 (Homo sapiens) [Search protein sequence]
NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY
TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVH
GVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY
GYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPR
LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITT
VLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFF
SQPARAAAIDRWSRIFFPVVFSFFNIVYWLYYV
3D structure
PDB6d6t Structure of a human synaptic GABAAreceptor.
ChainA
Resolution3.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ABU A Y157 F200 T202 Y205 Y150 F193 T195 Y198
BS02 Y01 A W319 F323 F324 W312 F316 F317
BS03 Y01 A F331 Y338 F324 Y331
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004890 GABA-A receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6d6t, PDBe:6d6t, PDBj:6d6t
PDBsum6d6t
PubMed29950725
UniProtP47870|GBRB2_HUMAN Gamma-aminobutyric acid receptor subunit beta-2 (Gene Name=GABRB2)

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