Structure of PDB 6d4a Chain A

Receptor sequence
>6d4aA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
NFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISR
DSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFR
MERGSTKYSYKSPQLSVHVTDLT
3D structure
PDB6d4a Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis.
ChainA
Resolution1.751 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FVP A F21 F117 R119 K126 Y127 S128 K130 F2 F98 R100 K107 Y108 S109 K111 MOAD: Kd=118uM
PDBbind-CN: -logKd/Ki=3.93,Kd=118uM
External links
PDB RCSB:6d4a, PDBe:6d4a, PDBj:6d4a
PDBsum6d4a
PubMed31369984
UniProtP20138|CD33_HUMAN Myeloid cell surface antigen CD33 (Gene Name=CD33)

[Back to BioLiP]