Structure of PDB 6d49 Chain A

Receptor sequence
>6d49A (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
GDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAI
ISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSY
FFRMERGSTKYSYKSPQLSVHVTDLT
3D structure
PDB6d49 Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis.
ChainA
Resolution1.801 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FVP A N20 F21 S68 F117 R119 K126 Y127 S128 K130 N4 F5 S52 F101 R103 K110 Y111 S112 K114 MOAD: Kd=118uM
PDBbind-CN: -logKd/Ki=3.93,Kd=118uM
External links
PDB RCSB:6d49, PDBe:6d49, PDBj:6d49
PDBsum6d49
PubMed31369984
UniProtP20138|CD33_HUMAN Myeloid cell surface antigen CD33 (Gene Name=CD33)

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