Structure of PDB 6d2n Chain A

Receptor sequence
>6d2nA (length=209) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
ALQQLFENNVRWAEAIKQEDPDFFAKLARQQTPEYLWIGCSDARVPANEI
VGMLPGDLFVHRNVANVVLHTDLNCLSVIQFAVDVLKVKHILVTGHYGCG
GVRASLHNDQLGLIDGWLRSIRDLAYEYREHLEQLPTEEERVDRLCELNV
IQQVANVSHTSIVQNAWHRGQSLSVHGCIYGIKDGLWKNLNVTVSGLDQL
PPQYRLSPL
3D structure
PDB6d2n Structural Mapping of Anion Inhibitors to beta-Carbonic Anhydrase psCA3 from Pseudomonas aeruginosa.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C42 D44 R46 H98 C101
Catalytic site (residue number reindexed from 1) C40 D42 R44 H96 C99
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C42 H98 C101 C40 H96 C99
BS02 FUS A C42 D44 H98 C101 G102 G103 C40 D42 H96 C99 G100 G101 MOAD: Ki=10uM
BindingDB: Ki=8000nM
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization

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Molecular Function
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Biological Process
External links
PDB RCSB:6d2n, PDBe:6d2n, PDBj:6d2n
PDBsum6d2n
PubMed30088334
UniProtQ9HVB9

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