Structure of PDB 6d12 Chain A

Receptor sequence
>6d12A (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
ATGPQFVSGVIVKIISTEPLPGRKQVRDTMAAISEVLYVDLLEGDTECHA
RFKTPLDALAVINAYTEINKKHCWKMEILSGDHEQRYWQKILVDRQAKLN
3D structure
PDB6d12 Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.
ChainA
Resolution2.205 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A P449 R468 R472 Y483 V484 D485 R496 Y532 I536 D539 R540 K543 P4 R23 R27 Y38 V39 D40 R51 Y87 I91 D94 R95 K98 PDBbind-CN: Kd=129nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6d12, PDBe:6d12, PDBj:6d12
PDBsum6d12
PubMed29946027
UniProtQ4G0J3|LARP7_HUMAN La-related protein 7 (Gene Name=LARP7)

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