Structure of PDB 6d05 Chain A

Receptor sequence
>6d05A (length=641) Species: 9606 (Homo sapiens) [Search protein sequence]
FRLYWDDLKRKLSEKLDSTDFTSTIKLLNENSYVPREAGSQKDENLALYV
ENQFREFKLSKVWRDQHFVKIQVKDSAQNSVIIVDKNGRLVYLVENPGGY
VAYSKAATVTGKLVHANFGTKKDFEDLYTPVNGSIVIVRAGKITFAEKVA
NAESLNAIGVLIYMDQTKFPIVNAELSFFGHAHLGTGDPYTPGFPSFNHT
QFPPSRSSGLPNIPVQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSE
SKNVKLTVSNVLKEIKILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKS
GVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGSVGATEWLEG
YLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTMQNVKHPVTG
QFLYQDSNWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCEDTDYPYLGTT
MDTYKELIERIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLL
SFVRDLNQYRADIKEMGLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRF
VMKKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSHTLPALLENLKLR
KQNNGAFNETLFRNQLALATWTIQGAANALSGDVWDIDNEF
3D structure
PDB6d05 Cryo-EM structure of an essential Plasmodium vivax invasion complex.
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A T310 F313 E465 E468 T191 F194 E346 E349
Gene Ontology
Molecular Function
GO:0004998 transferrin receptor activity
Biological Process
GO:0033572 transferrin transport

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6d05, PDBe:6d05, PDBj:6d05
PDBsum6d05
PubMed29950717
UniProtP02786|TFR1_HUMAN Transferrin receptor protein 1 (Gene Name=TFRC)

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