Structure of PDB 6czn Chain A

Receptor sequence
>6cznA (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
LSLTADQMVSALLDAEPPILYSSEASMMGLLTNLADRELVHMINWAKRVP
GFVDLTDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNKEGM
VEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSLEEKDHIHR
VLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYL
SDLLLEMLDAHR
3D structure
PDB6czn Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 V376 E380 M543 I43 V59 E63 M207
BS02 FNJ A A350 E353 W383 L387 M421 G521 H524 L525 A35 E38 W66 L70 M100 G194 H197 L198
External links
PDB RCSB:6czn, PDBe:6czn, PDBj:6czn
PDBsum6czn
PubMed
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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