Structure of PDB 6cyy Chain A

Receptor sequence
>6cyyA (length=330) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PMPFEEVRDFFYDRNNYIHDLDMAAERMFTESGMRTGGLDIQLAELMRDR
FGISVVIDDNLPDTAKRRYHPDTKVLRVAHWLMPGQRAFQIATQLALVGQ
SDLISSIVATDDQLSTEARGVARIGLANYFAGAFLLPYREFHRAAEQLRY
DIDLLGRRFGVGFETVCHRLSTLQRPRQRGIPFIFVRTDKAGNISKRQSA
TAFHFSRVGGSCPLWVVHDAFAQPERIVRQVAQMPDGRSYFWVAKTTAAD
GLGYLGPHKNFAVGLGCDLAHAHKLVYSTGVVLDDPSTEVPIGAGCKICN
RTSCAQRAFPYLGGRVAVDENAGSSLPYSS
3D structure
PDB6cyy Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor.
ChainA
Resolution2.506 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A Q237 F240 N279 Y280 E315 T316 H319 R338 K347 Q86 F89 N128 Y129 E164 T165 H168 R187 K196
BS02 SF4 A C363 P364 I443 G444 G446 C447 C450 C455 R458 C212 P213 I292 G293 G295 C296 C299 C304 R307
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6cyy, PDBe:6cyy, PDBj:6cyy
PDBsum6cyy
PubMed31504787
UniProtO06581|PRPR_MYCTU HTH-type transcriptional regulator PrpR (Gene Name=prpR)

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