Structure of PDB 6cwq Chain A

Receptor sequence
>6cwqA (length=308) Species: 376686 (Flavobacterium johnsoniae UW101) [Search protein sequence]
GAMSIFDKRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHL
SLAEKTAVKNSLLAIAQIEVAVKSFWGNIYEHFPKPEFNGLGSTFAECEF
RHSEAYSRLLEVLGYNDEFEKLLDVPVIRRRVDYLSNVLKDTKSQDNRKY
MVSLILFSILIENVSLFSQFAILLSFTRFKGYMKNVSNIIAWTSIDEQIH
ANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDILDWIFEEGE
IESIKKGDLVNFMKFRIDESLKQINIPVIFDVKVEDYKALAWFEEEVFAN
SLDDFFAK
3D structure
PDB6cwq Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor.
ChainA
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E67 E97 H100 E195 E69 E99 H102 E197
BS02 MN A E97 E160 E195 H198 E99 E162 E197 H200
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6cwq, PDBe:6cwq, PDBj:6cwq
PDBsum6cwq
PubMed29609464
UniProtA5FCJ5

[Back to BioLiP]