Structure of PDB 6cwp Chain A

Receptor sequence
>6cwpA (length=300) Species: 376686 (Flavobacterium johnsoniae UW101) [Search protein sequence]
MSIFDKRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSL
AEKTAVKNSLLAIAQIEVAVKSFWGNIYEHFPKPEFNGLGSTFAECEFRH
SEAYSRLLEVLGYNDEFEKLLDVPVIRRRVDYLSNVLKDTKSQDNRKYMV
SLILFSILIENVSLFSQFAILLSFTRFKGYMKNVSNIIAWTSIDEQIHAN
GGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDILDWIFEEGEIE
SIKKGDLVNFMKFRIDESLKQINIPVIFDVKVEDYKALAWFEEEVFANSL
3D structure
PDB6cwp Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor.
ChainA
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E67 E97 H100 E195 E67 E97 H100 E195
BS02 MN A E97 E160 E195 H198 E97 E160 E195 H198
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cwp, PDBe:6cwp, PDBj:6cwp
PDBsum6cwp
PubMed29609464
UniProtA5FCJ5

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