Structure of PDB 6csp Chain A

Receptor sequence
>6cspA (length=356) Species: 7955 (Danio rerio) [Search protein sequence]
ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPAR
LATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCA
LLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALT
ARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAF
FPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIARE
FAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILE
GGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAP
FWSSLR
3D structure
PDB6csp Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6.
ChainA
Resolution1.237 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D612 H614 D705 D170 H172 D263
BS02 FBM A H573 H574 G582 F583 D612 H614 F643 L712 Y745 H131 H132 G140 F141 D170 H172 F201 L270 Y303 MOAD: Kd=3nM
PDBbind-CN: -logKd/Ki=8.52,Kd=3nM
External links