Structure of PDB 6csc Chain A

Receptor sequence
>6cscA (length=437) Species: 9031 (Gallus gallus) [Search protein sequence]
ASSTNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYGGMRGMKG
LIYETSVLDPDEGIRFRGFSIPECQKLLPKAGGGEEPLPEGLFWLLVTGQ
IPTPEQVSWVSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNS
ESNFARAYAEGINRTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSI
GAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEGGNVSAHTSHL
VGSALSDPYLSFAAAMNGLAGPLHGLANQEVLLWLSQLQKDLGADASDEK
LRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPSDPMFKLV
AQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVS
RALGVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG
3D structure
PDB6csc Crystallographic Refinement and Atomic Models of Two Different Forms of Citrate Synthase at 2.7 And 1.7 A Resolution
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S244 H274 H320 R329 D375
Catalytic site (residue number reindexed from 1) S244 H274 H320 R329 D375
Enzyme Commision number 2.3.3.1: citrate (Si)-synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COF A R46 L273 H274 A277 V314 V315 G317 Y318 G319 H320 A321 K366 A367 K368 N373 R46 L273 H274 A277 V314 V315 G317 Y318 G319 H320 A321 K366 A367 K368 N373
Gene Ontology
Molecular Function
GO:0004108 citrate (Si)-synthase activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006101 citrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6csc, PDBe:6csc, PDBj:6csc
PDBsum6csc
PubMed
UniProtP23007|CISY_CHICK Citrate synthase, mitochondrial (Gene Name=CS)

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